达英-35及妈富隆治疗青春期多囊卵巢综合征的疗效

目的观察妈富隆与达英-35治疗青春期多囊卵巢综合征（PCOS）的临床疗效。方法将60例患者随机分为2组,A组给予妈富隆治疗,B组给予达英-35治疗,治疗3个周期后,复查女性激素6项,并记录患者月经、多毛及痤疮情况的变化,停药后随访3个月。结果两组患者经过治疗后,月经稀发、痤疮明显改善（P〈0.05）;治疗前后多毛改善均不明显（P〉0.05）。停药后,A组月经失调复发者8例,B组9例。结论妈富隆及达英-35对治疗青春期PCOS的月经失调均有良好疗效,妈富隆对LH/FSH值高的PCOS患者更合适,而达英-35对高雄激素血症的患者疗效更佳。

Efficacy of diane-35 and marvelon on adolescent polycystic ovary syndrome

Objective To observe the clinical efficacy of marvelon and diane-35 treatment for adolescent polycystic ovary syndrome.Methods 60 patients were randomly divided into two groups,group A received marvelon,group B received diane-35.After 3 cycles of treatment,we reexamined six kinds of female hormones and recorded patients′ menstruation,hirsutism and acne conditions change.Patients were followed up for 3 months after treatment.Results After treatment,patients′oligomenorrhea and acne of the two groups significantly improved（P〈0.05）,hirsutism was not significantly improved after treatment（P〈0.05）.There were 8 cases of recurrence of menstrual disorder in group A,and 9 cases in B group.Conclusion Marvelon and diane-35 have better effects on menstrual disorder caused by PCOS,marvelon is more appropriate for PCOS patients with high levels of LH / FSH,and diane-35 is better for patients with hyperandrogenism.