| 万拉法新与丁螺环酮治疗广泛性焦虑症对照研究 |
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| 引用本文： | 刘玉厚,徐敏秀,郑振宝. 万拉法新与丁螺环酮治疗广泛性焦虑症对照研究[J]. 精神医学杂志, 2003, 16(1): 19-21 |
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| 作者姓名： | 刘玉厚 徐敏秀 郑振宝 |
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| 作者单位： | 山东省临沂市精神卫生中心 276005(刘玉厚，徐敏秀)，山东省临沂市精神卫生中心 276005(郑振宝) |
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| 摘 要： | 目的 验证万拉法新治疗广泛性焦虑症的疗效及副反应。方法 对符合CCMD-2-R广泛性焦虑症诊断标准的患者，随机分为万拉法新组和丁螺环酮组治疗6周。于治疗前及治疗后1，2，4，5周末用汉密尔顿焦虑量表（HAMA），焦虑自评量表（SAS），临床总体评定量表（CGI）及副反应量表（TESS）评定临床疗效及副反应。结果 万拉法新与丁螺环酮疗效相当，起效时间相近，没有严重副反应。结论 万拉法新治疗广泛性焦虑症疗效确切，副反应少而轻，患者服药依从性好。
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| 关 键 词： | 广泛性焦虑症 万拉法新 丁螺环酮 |
| 文章编号： | 1009-7201(2003)-01-0019-03 |
A clinical control study of venlafaxine and buspirone in the treatment of general anxiety disorder. |
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| Liu Yuhou. Xu Minxiu,Zheng Zhenbao,Linyi Mental Health Center,Shandong ,China. A clinical control study of venlafaxine and buspirone in the treatment of general anxiety disorder.[J]. Journal of Psychiatry, 2003, 16(1): 19-21 |
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| Authors: | Liu Yuhou. Xu Minxiu Zheng Zhenbao Linyi Mental Health Center Shandong China |
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| Affiliation: | Liu Yuhou. Xu Minxiu,Zheng Zhenbao,Linyi Mental Health Center,Shandong 276005,China |
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| Abstract: | Objective To verify the clinical efficacy and the side effects of venlafaxine in the treatment of general anxiety disorder. Methods 68 patients meeting CCMD-2-R criteria for general anxiety disorder were randomly assigned to venlafaxine group(n = 35) and buspirone group(n = 33)for 6 weeks. Effects and side effects were evaluated with Hamilton Anxiety Seale(HAMA),Self-Rating Anxiety Scale(SAS) Clinical Global Impression Scale(CGI)and Treatment Emergent Symptoms Scale(TESS)before and after 1,2,4, 6-weeks treatment respectively. Results The therapeutic efficacy in venlafaxine group was similar to that in buspirone. Compared with buspirone , venlafaxine had few side effects. Conclusion It is suggested that venlafaxine was effective in the treatment of general anxiety disorder and produced fewer side effects. |
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| Keywords: | General anxiety disorder Venlafaxine Buspirone |
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