| 山青之片对大鼠血脂影响的实验研究 |
| |
| 引用本文： | 杨岚,唐礼可,赵岩,郭殿武,吴耀东,朱红卫.山青之片对大鼠血脂影响的实验研究[J].心脑血管病防治,2009,9(6):422-423. |
| |
| 作者姓名： | 杨岚 唐礼可 赵岩 郭殿武 吴耀东 朱红卫 |
| |
| 作者单位： | 1. 杭州民生药业集团有限公司产品开发部,浙江,杭州,310011
2. 南京医科大学,江苏,南京,210029 |
| |
| 摘 要： | 目的:观察山青之片的抑制血脂升高作用。方法:将SD大鼠随机分为对照组和低、中、高剂量给药组。低、中、高剂量分别0.2g/kg、0.4g/kg、1.2g/kgBW/d。经口给药30天后采血,检测血清TC、TG、HDL-C三项血脂指标。结果:与对照组相比,中、高剂量组能明显抑制大鼠血清TC及TG含量的升高,有显著性差异(P<0.05)。结论:一定剂量的山青之片可能具有抑制血脂升高的作用。
|
| 关 键 词： | 山青之 赤芍 党参 降血脂 大鼠 |
Reducing Blood Lipids Effect of Shanqingzhi in Rats |
| |
| Institution: | YANG Lan, TANG Li-ke, ZHAO Yan, et al. (Hangzhou Minsheng Pharmacevtical Co. Ltd. , Zhejiang 310011, China) |
| |
| Abstract: | Objective To observe the reducing blood lipids effect of Shanqingzhi in rats. Methods Modeled high blood lipids SD rats were randomly divided into 4 groups. Given orally drug Shanqingzhi 0.2,0.4,1.2g/ kgBw/d, respectively to above 3 groups for 30 days（low, middle and high dose groups, respectively）. And the other group served as control group （rats were not given drug Shanqingzhi）. After 30 days treatment, the blood lipids （serum TC, TG） of all rats were measured. Results Compared with control group, serum TC in middle and high dose groups were very sigruficantly reduced （P 〈 0.01） and serum TG in middle and high dose groups were significantly reduced （P 〈 0.05）. Conclusions Shanqingzhi can significantly reduce blood lipids in modeled high blood lipids rats. |
| |
| Keywords: | Shanqingzhi Radix Paeoniae Rubra Radix Cedonopsis pilosula Blood lipids Rat |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
