多聚酶链反应检测尿中结核杆菌的临床意义

应用多聚酶链反应（ＰＣＲ）对８６例患者（１０例经病理诊断为肾结核，６９例可疑肾结核，７例单纯附睾结核）和３０例健康对照者进行连续２日晨尿结核菌检测。１０例肾结核患者检出均阳性；可疑肾结核者第一次检出９例，第二次为６例；７例附睾结核者两次无一阳性；对照组有１例二次检查均为阳性。认为ＰＣＲ对尿中结核杆菌检出率高、准确、快速，值得在临床上推广应用。

Detection of mycobacterium tuberculosis in urine by polymerase chain reaction

Mycobacterium tuberculosis in urine was assayed by polymerase chain reaction(PCR)for 86 patients(10 renal tuberculosis,69 suspected renal tuberculosis and 7 epididymis tuberculosis) with 30 healthy individuals served as controls.2 sucessive assays were performed for each and both were positive in all the 10 renal tuberculosis patients.the first assay was positive in 9 and thesecond in 6 of the 69 suspected cases. None of the 7 epididymis tuberculosis was positive. It was positive in only one of the 330 healthy controls.Detection of mycobacterium tuberculosis in urineby PCR was claimed to be sensitive,accurate and fast and was recommended for clinical application.