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Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C |
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| Authors: | Cario Elke Gerken Guido Podolsky Daniel K |
| Institution: | Division of Gastroenterology and Hepatology, University Hospital of Essen, Germany. elke.cario@uni-essen.de |
| Abstract: | |
| Keywords: | AP-1 activator protein-1 FITC fluorescein isothiocyanate IEC intestinal epithelial cell LPS lipopolysaccharide MARCKS myristoylated alanine-rich C kinase substrate PGN peptidoglycan PKC protein kinase C PMA phorbol 12-myristate 13-acetate TER transepithelial resistance TJ tight junction TLR Toll-like receptor TLR2DN dominant-negative construct of Toll-like receptor 2 TLR4DN dominant-negative construct of Toll-like receptor 4 ZO-1 zonula occludens-1 |
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