| 薄层扫描法测定金蝉口服液中黄芩苷的含量 |
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| 引用本文： | 薛满,闵春艳.薄层扫描法测定金蝉口服液中黄芩苷的含量[J].抗感染药学,2008,5(2):82-85. |
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| 作者姓名： | 薛满 闵春艳 |
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| 作者单位： | 江苏苏州药品检验所,江苏,苏州,215002 |
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| 摘 要： | 目的：测定金蝉口服液中黄芩苷的含量，建立金蝉口服液的质量控制方法。方法：用聚酰胺薄膜分离金蝉口服液中黄芩苷，薄层扫描法测定其含量；以φ（C2H2O2，HAC）=36％作展开剂；采用双波长反射法锯齿扫描，检测波长（λs=278nm，λR=370nm）。结果：黄芩苷点样量在0．217～1．083μg／mL范围内呈良好的线性关系，回归方程：A=2131．551＋7．545C，r=0．9993，平均加样回收率：101．60％，RSD=2．50％（n=5）。结论：该方法准确、简便．适合该制剂中黄芩苷的含量测定。
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| 关 键 词： | 金蝉口服液 黄芩苷 含量测定 薄层扫描法 |
Determination of Baicalin in Jinchan Oral Liquid by TLC Scanning |
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| XUE Man,MIN Chun-yan.Determination of Baicalin in Jinchan Oral Liquid by TLC Scanning[J].Anti-infection Pharmacy,2008,5(2):82-85. |
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| Authors: | XUE Man MIN Chun-yan |
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| Institution: | (Suzhou institute for drug control, Suzhou Jiangsu 215002, China) |
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| Abstract: | Objective:To establish a method for quality control of Jinchan oral liquid,the content of Baicalin in Jinchan oral liquid was determined by thin layer chromatographic scanning(TLCS).Methods:Baicalin of Jinchan oral liquid was separated byφ(C_2H_4O_2,HAC)=36% acids in polyamide film;the method of the dual wavelength TLCS was adopted to determine the content of baicalin in Jinchan oral liquid and the detection wave-length wasλ_2=278 nm,λ_R= 370 nm.Results:The content of baicalin between 0.217～1.083μg/mL showed a good linearity.The equation of linear regression was A=2 131.551+7.545 C,r=0.999 3.The average recovery was 101.60% and RSD was 2.50%(n=3). Conclusion:This method is accurate and simple.It can be used to determine baicalin in Jinchan oral liquid. |
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| Keywords: | Jinchan oral liquid baicalin TLCS determination of baicalin TLCS |
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