| IGF-1、IR对老年高血压及糖尿病影响的研究 |
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| 引用本文： | 庞明,梁积英,史文,苏卫红,万里凯.IGF-1、IR对老年高血压及糖尿病影响的研究[J].广西医科大学学报,2004,21(1):13-14. |
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| 作者姓名： | 庞明 梁积英 史文 苏卫红 万里凯 |
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| 作者单位： | 广西壮族自治区江滨医院,南宁,530021;广西壮族自治区江滨医院,南宁,530021;广西壮族自治区江滨医院,南宁,530021;广西壮族自治区江滨医院,南宁,530021;广西壮族自治区江滨医院,南宁,530021 |
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| 基金项目： | 广西区科技厅自然科学基金资助课题 (桂科自 0 0 0 70 45 ) |
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| 摘 要： | 目的：探讨胰岛素样生长因子(IGF-1)、胰岛素抵抗(IR)对老年原发性高血压(EH)及糖尿病(DM)的影响。方法：将90例老年高血压患者随机分为3组，其中单纯EH32例，EH伴左室肥厚(EH-LVH)28例，EH伴糖尿病(EH DM)30例。2型糖尿病(DM)30例。正常老年人对照组30例．均检测IGF-1和胰岛素(INS)。90例高血压和对照组同时做心脏超声检查，比较各组的IGF-1和IR。结果：EH组、EH DM组、EH LVH和DM组的IGF-1、IR均高于对照组。结论：IGF-1和IR可能是老年高血压和糖尿病的共同起病因素之一。
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| 关 键 词： | 胰岛素样生长因子 胰岛素抵抗 老年原发性高血压 糖尿病 |
| 修稿时间： | 2003年11月12 |
THE EFFECTS OF IGF-1,IR ON THE ELDERLY ESSENTIAL HYPERTENSION AND TWO TYPES OF DIABETES |
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| Pang Ming,Liang Jiying,Shi Wen,et al..THE EFFECTS OF IGF-1,IR ON THE ELDERLY ESSENTIAL HYPERTENSION AND TWO TYPES OF DIABETES[J].Journal of Guangxi Medical University,2004,21(1):13-14. |
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| Authors: | Pang Ming Liang Jiying Shi Wen |
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| Abstract: | Objective:To discuss the effects of serum insulin-like growth factor-1(IGF-1) and insulin resistance (IR) for occurancity essential hypertension in the aged and two types of diabetes mellitus(DM).Methods:Ninety cases with EH were divided into three subgroups: pure EH(n=32), EH+LVH(n=28) and EH+DM(n=30). Other two types of diabetes in 30 cases and thirty normal subjects were studied by measuring IGF-1 and IR. Ninety cases EH and thirty normal subjects were studied by echocardiography.Result:IGF-1 and IR in four groups of EH, EH+LVH, EH+DM and DM increased more significantly than the normal group(P<0.01), and there was a positive correlation between the serum IGF-1 and development of left ventricular hypertrophy.Conclusion:The increased serum IGF-1 and IR may be common attacking factor of hypertension and diabetes. |
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| Keywords: | insulin-like growth factor-1(IGF-1) insulin resistance (IR) aged essential hypertension diabetes |
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