慢性扁桃体炎与过敏性紫癜的关系探讨

目的 探讨儿童慢性扁桃体炎与过敏性紫癜的关系.方法 选择过敏性紫癜伴有慢性扁桃体炎患儿56例,其中行扁桃体切除术26例（手术组）,未行扁桃体切除术30例（非手术组）,对两组腹痛持续时间、皮疹持续时间、尿蛋白转阴时间、尿潜血转阴时间、抗链球菌溶血素“O”（ASO）滴度、补体C3情况进行检测比较,并对手术组患儿手术前后24 h尿蛋白定量、尿红细胞数进行检测比较.结果 手术组患儿皮疹持续时间、腹痛持续时间、尿蛋白转阴时间、尿潜血转阴时间均优于非手术组（10.58±4.22）d比（16.70±9.68）d、（6.49±2.45）d比（9.20±2.21）d、（12.3±4.1）d比（16.5±5.6）d、（10.1±3.3）d比（12.7±4.9）d],差异有统计学意义（P＜ 0.01或＜0.05）.两组ASO滴度和补体C3比较差异无统计学意义（P＞0.05）.手术组术后24 h尿蛋白定量、尿红细胞数均较术前明显好转（0.72±0.28）g比（1.61±1.22）g、（14.95±4.76）个/μl比（56.61±12.57）个/μl],差异有统计学意义（P＜0.01）.结论 慢性扁桃体炎是导致过敏性紫癜皮疹反复并诱发紫癜性肾炎的重要因素之一,扁桃体切除术是治疗过敏性紫癜伴有慢性扁桃体炎且皮疹反复患儿的可选手段.

Relationship between chronic tonsillitis and allergic purpura

Objective To explore the relationship between chronic tonsillitis and allergic purpura.Methods Fifty-six allergic purpura children with chronic tonsillitis were selected,26 children were given tonsillectomy （operation group）,and 30 children were not given tonsillectomy （no-operation group）.The duration of abdominal pain,duration of erythra,proteinuria negative time,hematuria negative time,antistreptolycin ＆quot;O＆quot; rite,complement C3 were compared between the 2 groups,and the 24 h urine protein quantitarion and urine red blood cell count in operation group were compared between preoperative and postoperative.Results The duration of erythra,duration of abdominal pain,proteinuria negative time,hematuria negative time in operation group were significantly better than those in no-operation group （10.58 ±4.22） d vs.（16.70 ±9.68） d,（6.49 ±2.45） d vs.（9.20 ± 2.21） d,（12.3 ±4.1） d vs.（16.5 ± 5.6） d,（10.1 ± 3.3） d vs.（12.7 ± 4.9） d],there were statistical differences （P 〈 0.01 or 〈 0.05）.There were no statistical differences in antistreptolycin ＆quot;O＆quot; tite and complement C3 between the 2 groups （P〉 0.05）.In operation group,the 24 h urine protein quantitation and urine red blood cell count postoperative were significantly better than preoperative （0.72 ± 0.28） g vs.（1.61 ± 1.22） g,（14.95 ± 4.76） / μ l vs.（56.61 ± 12.57）/μ 1],there were statistical differences （P〈 0.01）.Conclusion Chronic tonsillitis is one of the important factors which can make allergic purpura erythra relapses and induce purpura nephritis,and tonsillectomy is the optional means of treatment of purpura nephritis with chronic tonsillitis and erythra relapses.