双波长薄层扫描法测定复方布洛芬片中主药的含量

建立了复方布洛芬片的双波长薄层扫描测定方法，研究了薄层色谱条件、薄层散射作用及扫描条件对薄层色谱扫描的影响。采用硅胶ＧＦ２５４－０．７５％ＣＭＣ－Ｎａ薄层板，以乙酸乙酯－甲醇－氨水（７５：１５：１０）为展开剂，用岛津ＣＳ－９０００型薄层扫描仪，双波长反射法锯齿扫描，以随行外标二点法定量对样品进行了分析，布洛芬和伪麻黄碱的回收率分别为１００．２％和１０１．９％，ＲＳＤ〈３．３％（ｎ＝５），三个批号的

Assay of Ibuprofen and Pseudoephedrine Contained in Compound Ibuprofen Tablet by Dual Wavelength Thin-Layer Scanning Technique

A method of quantitative analysis for ibuprofen and pseudoe phedrine coritained in compound ibuprofen tablet by dual-wavelength thin-layer scanning technique was developed.The sample solution was spotted on siliea gel GF254-plate and developed by ethyl acetate-methanol-amonia water(75:15:10) at room temperature.The spots were scanned with Shimadzu CS-9000 Dualwavelength TLC Scanner in reflection mode zig-zag seanning.The recoveries were 100.2% for ibuprofen and 101.9% for pseudoephedrine.Three samples were analyzed by the proposed methed,and the results well agreed with those obtained by HPLC and their relative standard deviations were less tharn 3.3% (n=5).