Evaluation of three molecular assays for rapid identification of methicillin-resistant Staphylococcus aureus |
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Authors: | Francois Patrice Bento Manuela Renzi Gesuele Harbarth Stephan Pittet Didier Schrenzel Jacques |
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Affiliation: | Department of Internal Medicine, Service of Infectious Diseases/Genomic Research Laboratory, University of Geneva Hospitals, CH-1211 Geneva 14, Switzerland. patrice.francois@genomic.ch |
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Abstract: | One home-developed assay and two commercial assays for the rapid identification of methicillin-resistant Staphylococcus aureus (MRSA) were compared by use of a collection of clinical isolates displaying highly diverse genetic backgrounds. Our results suggest that users of orfX-staphylococcal cassette chromosome mec-based assays should repeatedly monitor the local epidemiology to minimize the risks of detection bias and the omission of emerging MRSA clones. |
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