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| Galectin-3蛋白在甲状腺肿瘤中的表达及其意义 | |
| 引用本文： | 王丽华,赵咏桔,王晓颖,郑林,肖家诚,徐锦屏,罗邦尧.Galectin-3蛋白在甲状腺肿瘤中的表达及其意义[J].中华内分泌代谢杂志,2004,20(4):300-302. |
| 作者姓名： | 王丽华 赵咏桔 王晓颖 郑林 肖家诚 徐锦屏 罗邦尧 |
| 作者单位： | 1. 200025,上海第二医科大学附属瑞金医院内分泌代谢病科,上海市内分泌代谢病临床医学中心,上海市内分泌代谢病研究所 2. 瑞金医院病理科 3. 上海第二医科大学基础医学院病理教研室 4. 浙江省台州市中心医院病理科 |
| 摘 要： | 用免疫组化ABC法检测甲状腺良恶性肿瘤组织中Galectin3蛋白的表达,发现甲状腺癌组织的表达率明显高于癌旁组织、结节性甲状腺肿和甲状腺腺瘤组织的表达率,提示Galectin3蛋白是甲状腺癌,尤其是滤泡上皮起源的甲状腺癌的良好的肿瘤指标,有一定的临床应用价值。 |
| 关 键 词： | 半乳凝素3 甲状腺肿瘤 免疫组织化学 |
| 修稿时间： | 2003年3月18日 |
Expression of galectin-3 in thyroid tumors and its implication |
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| WANG Li-hua,ZHAO Yong-ju,WANG Xiao-ying,ZHENG Lin,XIAO Jia-cheng,XU Jin-ping,LUO Bang-yao.Expression of galectin-3 in thyroid tumors and its implication[J].Chinese Journal of Endocrinology and Metabolism,2004,20(4):300-302. | |
| Authors: | WANG Li-hua ZHAO Yong-ju WANG Xiao-ying ZHENG Lin XIAO Jia-cheng XU Jin-ping LUO Bang-yao |
| Institution: | WANG Li-hua~*,ZHAO Yong-ju,WANG Xiao-ying,ZHENG Lin,XIAO Jia-cheng,XU Jin-ping,LUO Bang-yao. ~*Shanghai Clinical Center for Endocrine and Metabolic Diseases,Shanghai Institute of Endocrine and Metabolic Diseases,Ruijin Hospital,Shanghai Second Medical University,Shanghai 200025 |
| Abstract: | Galectin-3 protein expression was assayed by immunohistochemical method in benign and malignant thyroid tumors. The result showed that the majority of thyroid carcinomas expressed galectin-3 protein. In contrast, few benign thyroid adenomas and multinodular goiters expressed this protein. Thus, galectin-3 may be used as a marker of malignancy in thyroid tumors. |
| Keywords: | Galectin-3 Thyroid neoplasms Immunohistochemistry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |