经尿道膀胱肿瘤电切术后膀胱灌注吡柔比星治疗浅表性膀胱肿瘤42例报告

目的探讨吡柔比星膀胱灌注对治疗浅表性膀胱癌术后复发的预防效果。方法42例患者，在行经尿道膀胱肿瘤电切术（TURBt）术后定期经导尿管给予膀胱内灌注吡柔比星30mg／40ml，每周1次，每次膀胱内保留60min，共8次，术后3个月行1次膀胱镜检查。结果共有4例复发。42例患者有不同程度的膀胱区不适，3例症状较重。结论吡柔比星膀胱内灌注预防肿瘤术后复发疗效显著、安全、可靠。

Prevention and treatment of superficial bladder tumor by bladder perfusion of pirarubicin after transurethral bladder tumor electrosection(report of 42 cases)

Objective To discuss the effectiveness of bladder perfusion of pirarubicin to prevent recurrence after superficial bladder carcinoma surgery. Method Pirarubicin （30 mg/40 ml）was perfused to the bladder through urinary catheter for 42 patients after transurethral resection of bladder tumor （TURBt） periodically, i. e. once per week, and was retained in the bladder for 60 min every time, for 8 times together. A cystoscopic examination was taken 3 months after operation. Result Recurrence occurred in 4 cases in total. All 42 patients had more or less uncomfortable feeling in bladder,in which 3 patients had relatively serious symptoms. Conclusion Application of bladder perfusion of pirarubicin is effective, safe and reliable for prevention of superficial bladder tumor after TURBt.