| 双环醇治疗非酒精性脂肪性肝炎的临床观察 |
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| 引用本文： | 李方学,张为卿,李莉,张广蕾,何荣梅,江波.双环醇治疗非酒精性脂肪性肝炎的临床观察[J].首都医药,2011(14):31-32. |
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| 作者姓名： | 李方学 张为卿 李莉 张广蕾 何荣梅 江波 |
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| 作者单位： | 贵州省黔西南州人民医院,562400 |
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| 摘 要： | 目的探讨双环醇治疗非酒精性脂肪性肝炎(NASH)的临床疗效及安全性。方法 136例NASH患者随机分为治疗组72例与对照组64例。两组均在适当休息、控制饮食、降低体重的基础上,治疗组服用双环醇片25mg,Tid,疗程6月;对照组服用水飞蓟宾70mg,Tid,疗程6月。观察两组治疗前后患者症状、肝脏彩超及血生化指标变化。结果治疗组肝区不适、纳差、乏力、腹胀改善情况优于对照组(P<0.05),两组均能明显降低ALT、AST、TC、LDL-C、FBG并减轻肝脏彩超脂肪变性,但在降低TG、GGT方面治疗组优于对照组(P<0.05)。结论双环醇能有效改善NASH患者的临床症状、血生化指标及其肝脏影像学表现,临床应用过程中未发生明显不良反应。
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| 关 键 词： | 双环醇 非酒精性 脂肪性肝炎 临床观察 |
Bicyclol treatment of non-alcoholic steatohepatitis clinical research |
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| LI Fang Xue,ZHANG Wei Qin,LI Li,ZHANG Guang Lei,HE Rong Mei,JIANG Bo.Bicyclol treatment of non-alcoholic steatohepatitis clinical research[J].Capital Medicine,2011(14):31-32. |
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| Authors: | LI Fang Xue ZHANG Wei Qin LI Li ZHANG Guang Lei HE Rong Mei JIANG Bo |
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| Institution: | LI Fang Xue,ZHANG Wei Qin,LI Li,et al.JIANG Bo.(the Second Division of Qianxinan People's Hospital of Guizhou Province.Xing Yi 562400) |
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| Abstract: | Objective Bicyclol treatment of non-alcoholic steatohepatitis(NASH) Clinical efficacy and safety.Methods 136 cases of NASH in patients with 72 patients randomly divided into treatment group and control group in 64.Both groups were proper rest,diet,weight loss based on the treatment group taking bicyclol 25mg,Tid,Course in June.The control group taking silybin 70mg,Tid,Course in June.Symptoms were observed before and after treatment,liver ultrasonography and blood biochemical changes.Result Treatment of live... |
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| Keywords: | non-alcoholic steatohepatitis bicyclol clinical study |
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