| 塞克硝唑凝胶剂的研制与含量测定 |
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| 引用本文： | 薛大权,谢云,梅红武,屠俊文. 塞克硝唑凝胶剂的研制与含量测定[J]. 医药导报, 2002, 21(9): 578-579 |
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| 作者姓名： | 薛大权 谢云 梅红武 屠俊文 |
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| 作者单位： | 1. 湖北药检高等专科学校,武汉,430064
2. 湖北省鄂州市第一人民医院,436000 |
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| 摘 要： | 目的:制备塞克硝唑凝胶剂并建立含量测定方法.方法:应用聚羧乙烯941作辅料制备塞克硝唑凝胶剂,用一阶导数分光光度法测定凝胶剂中塞克硝唑的含量;结果:塞克硝唑凝胶剂平均回收率99.9%,RSD 0.206%.结论:聚羧乙烯可作为辅料制备塞克硝唑凝胶剂,一阶导数分光光度法测定准确可靠.
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| 关 键 词： | 塞克硝唑凝胶剂 一阶导数分光光度法 含量测定 |
| 文章编号： | 1004-0781(2002)09-0578-02 |
| 修稿时间： | 2002-02-19 |
Preparation and Content Determination of Secnidazole Gel |
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| XUE Da quan ,XIE Yun ,MEI Hong wu ,TU Jun wen. Preparation and Content Determination of Secnidazole Gel[J]. Herald of Medicine, 2002, 21(9): 578-579 |
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| Authors: | XUE Da quan XIE Yun MEI Hong wu TU Jun wen |
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| Affiliation: | XUE Da quan 1,XIE Yun 1,MEI Hong wu 2,TU Jun wen 2 |
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| Abstract: | Objective:To prepare a secnidazole gel and set up a method of its content determination. Method:Carboxyvinyl polymer 941 as the excipient in the preparation of the gel, and first order derivative spectrophotometry was used in the content determination of the gel. Results:The gel prepared was even and stable, with an average rate of recovery of 99.9% ( RSD 0.206%). Conclusion:Carboxyinyl polymer may serve as the excipient in the preparation of secnidazol gel. Determination of the content with first order derivative spectrophotometry was accurate and reliable. |
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| Keywords: | Secnidazole gel First order derivative spectrophotometry Content determination |
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