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β‐mangostin suppresses human hepatocellular carcinoma cell invasion through inhibition of MMP‐2 and MMP‐9 expression and activating the ERK and JNK pathways
Authors:Chien‐Feng Huang  Ying‐Hock Teng  Fung‐Jou Lu  Wen‐Hung Hsu  Chia‐Liang Lin  Chia‐Chen Hung  Jai‐Nien Tung  Yi‐Hsien Hsieh  Chung‐Jung Liu
Affiliation:1. Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan;2. Department of Critical Care Medicine, Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan;3. Department of Emergency Medicine, School of Medicine, Chung Shan Medical University, Taichung, Taiwan;4. Department of Emergency Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan;5. School of Medical Applied Chemistry, Chung Shan Medical University, Taichung, Taiwan;6. Department of Internal Medicine, Division of Gastroenterology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan;7. Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University, Taichung, Taiwan;8. Department of Neurosurgery, Tungs'Taichung MetroHarbor Hospital, Taichung, Taiwan;9. Department of Biochemistry, School of Medicine, Chung Shan Medical University, Taichung, Taiwan;10. Clinical laboratory, Chung Shan Medical University Hospital, Taichung, Taiwan;11. Center for Stem Cell Research, Kaohsiung Medical University, Kaohsiung, Taiwan
Abstract:
Keywords:β  ‐Mangostin  hepatocellular carcinoma cell  invasion  migration  MMP‐2  MMP‐9
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