| 豨桐滴丸和豨桐胶囊的溶出度对比研究 |
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| 引用本文： | 周 昊,李志焕,史德胜. 豨桐滴丸和豨桐胶囊的溶出度对比研究[J]. 医学教育探索, 2012, 27(2): 114-116 |
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| 作者姓名： | 周 昊 李志焕 史德胜 |
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| 作者单位： | 天津医科大学总医院，天津 300052;天津中新药业集团股份有限公司药材公司，天津 300079;天津丹溪国药研究所，天津 300061 |
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| 摘 要： | 目的 对豨桐滴丸和胶囊进行溶出度的比较。方法 采用HPLC法测定样品中奇壬醇，并以此为指标比较了豨桐滴丸和胶囊在水、0.1 mol/L HCl、0.5%十二烷基硫酸钠中的溶出度。结果 在30 min时，豨桐滴丸在3种不同介质的溶出度达到81.24%、80.24%、88.72%，而豨桐胶囊只有71.35%、70.35%、76.95%。结论 豨桐滴丸中奇壬醇的溶出明显优于豨桐胶囊。
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| 关 键 词： | 豨桐滴丸；豨桐胶囊；溶出度；奇壬醇；高效液相色谱 |
Comparison on dissolution between Xitong Dropping Pills and Xitong Capsule |
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| ZHOU Hao,LI Zhi-huan and SHI De-sheng. Comparison on dissolution between Xitong Dropping Pills and Xitong Capsule[J]. Researches in Medical Education, 2012, 27(2): 114-116 |
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| Authors: | ZHOU Hao LI Zhi-huan SHI De-sheng |
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| Affiliation: | Tianjin Medical University General Hospital, Tianjin 300052, China;Tianjin Zhongxin Pharmaceutical Group Co., Ltd. Traditional & Herbal Medicine Company, Tianjin 300079, China;Tianjin Danxi Traditional Chinese Medicine Institute, Tianjin 300061, China |
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| Abstract: | Objective To compare the dissolution of Xitong Dropping Pills and Xitong Capsule. Methods Contents of kirenol in Xitong Dropping Pills and Xitong Capsule were determined by HPLC, and the dissolutions in three different dissolution media water, 0.1 mol/L HCl, and 0.5% sodium dodecyl sulfate (SDS) were compared. Results The dissolutions of kirenol in Xitong Dropping Pills in three different dissolution media were 81.24%, 80.24%, and 88.72% in 30 min, while the dissolutions of Xitong Capsule were 71.35%, 70.35%, and 76.95%, respectively. Conclusion The dissolution of kirenol in Xitong Dropping Pills is higher than that in Xitong Capsule |
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| Keywords: | Xitong Dropping Pills Xitong Capsule dissolution kirenol HPLC |
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