2003～2004年南昌市泌尿生殖道支原体的耐药分析

目的了解南昌地区STD门诊患者泌尿生殖道支原体感染及耐药情况，为临床治疗提供参考依据。方法应用法国生物梅里埃公司的IST2试剂盒进行支原体培养＋药敏检测：结果原始霉素（95.5％）、交沙霉素（91．8％）、强儿霉素（90％）、四环素（81．9％）对Uu的敏感性很强，其次是克拉毒素（63．9％）。阿奇毒素为常用抗生素，但敏感半仅为（42．4％），而氧氟沙星（10．8％）和环丙沙星（1．8％）对Uu的敏感性相对较低：结论原始霉素、交沙霉素、强力霉素、四环素等应作为本地区目前治疗泌尿生殖道支原体感染的首选抗生素。

Analysis of drug resistance of mycoplasma in genitourinary tract in Nan Chang from 2003 to 2004

Objective To research infection and drug resistance of mycoplasma in genitourinary tract among the STD outpatients of Nan Chang and provide reference for the clinical treatment. Methods To carry out the mycoplasma culture and drug sensitive test with IST2 kit from Bio-Merieux, France. Results Pristamycin (95.5%), josamycin (91.8%), doxycycline (90%) and tetracycline (81.9%) were very sensitive to ureaplasma urealyticum (Uu), and the next was clarithromycin (63.9%). The azithromycin was the commonly-used antibiotic, but 42.4% only at sensitiveness. The ofloxacin (10.8%) and ciprofloxacin (1.8%) were of relatively lower sensitiveness to Uu. Conclusion Pristamycin, josamycin, doxycycline and tetracycline must be the preferred antibiotics for the treatment of mycoplasma infection in genitourinary tract now in the local area.