| 谷氨酸免疫抑制作用的研究 |
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| 引用本文： | 毕爱华,王立人,叶嗣颖,黄庆华,朱熹智. 谷氨酸免疫抑制作用的研究[J]. 华中科技大学学报(医学版), 1985, 0(6) |
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| 作者姓名： | 毕爱华 王立人 叶嗣颖 黄庆华 朱熹智 |
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| 作者单位： | 同济医科大学基础医学部微生物学教研室(毕爱华，王立人，叶嗣颖，黄庆华)，同济医科大学基础医学部微生物学教研室(朱熹智) |
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| 摘 要： | 本文在实验动物体内和体外进行了谷氨酸的免疫抑制作用研究。谷氨酸对耳肿反应、外周血中T细胞数、淋巴细胞转化反应及特异性抗体形成(红细胞溶解分光光度法,QHS)均有明显抑制作用,并能延长小鼠同种移植物的存活时间。谷氨酸有希望成为一种低毒有效的免疫抑制剂。
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| 关 键 词： | D-谷氨酸 L-谷氨酶 谷氨酸钠 免疫抑制剂 |
Study on the Immimosuppressive Effect of Glutamic Acid |
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| Bi Aihua,Wang Liren,Ye Siying,Huang Qinghua,Zhu Xizhi. Study on the Immimosuppressive Effect of Glutamic Acid[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 1985, 0(6) |
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| Authors: | Bi Aihua Wang Liren Ye Siying Huang Qinghua Zhu Xizhi |
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| Affiliation: | Bi Aihua,Wang Liren,Ye Siying,Huang Qinghua,Zhu XizhiDepartment of Microbiology,Faculty of Basic Medical Sciences,Tongji Medical University,Wuhan |
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| Abstract: | The immunosuppressive effect of glutamic acid was studied in experimental animals and in vitro.The glutamic acid showed definite inhibitory action against development of ESR,peripheral blood T cells,lymphocyte transformation reaction and specific antibody formation,(QHS reaction) and prolong the survival of allografts in mice.These drugs will become low toxic effective immunosuppressive agents in the future. |
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| Keywords: | D-glutamic acid L-glutamic acid Sod. glutamate Immunosuppressive agent |
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