| 维生素E和维生素C对HL-60细胞NO生成的影响 |
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| 引用本文： | 杨莉萍. 维生素E和维生素C对HL-60细胞NO生成的影响[J]. 海南医学, 2007, 18(5): 139-140 |
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| 作者姓名： | 杨莉萍 |
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| 作者单位： | 广东医药学院门诊部,广东,广州,510224 |
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| 摘 要： | 目的 探讨维生素E和维生素C对HL-60细胞NO生成的影响.方法 用不同浓度的维生素E和维生素C作用HL-60细胞,采用Criess反应测定细胞培养上清液的NO2-量,间接反映细胞的NO生成量.结果 随着抗坏血酸浓度增高,HL-60细胞NO生成并无减少,高浓度时NO生成增加(P＜0.01);而随着维生素E浓度增高,HL-60细胞NO生成减少(P＜0.01).结论 维生素E显著地抑制HL-60细胞NO生成,说明维生素E在抗肿瘤细胞增生作用中可能起着重要的作用.
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| 关 键 词： | 维生素E 维生素C:HL-60细胞 NO |
| 文章编号： | 1003-6350（2007）05-139-02 |
Effects of vitamin E and vitamin C on NO production in HL-60 cell |
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| YANG Li-ping. Effects of vitamin E and vitamin C on NO production in HL-60 cell[J]. Hainan Medical Journal, 2007, 18(5): 139-140 |
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| Authors: | YANG Li-ping |
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| Affiliation: | Out-Patient department of Guangdong Pharmaceutical University, Guangzhou, 510224, China |
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| Abstract: | Objective To investigate the effects of vitamin E and vitamin C on NO production in HL-60 cell. Methods Griess reaction was used to detect respectively the NO2content in supernatant of cultured cells with effects of vitamin E and vitamin C in different concentrations. Results NO production did not change much,but increased with vitamin C in high concentration (p<0.01). NO production was inhibited obviously according to the increasing concentration of vitamin E (p<0.01). Conclusions Vitamin E may play an important role in antitumor proliferation since it can remarkably inhibit NO production in HL-60 cell. |
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| Keywords: | Vitamin E Vitamin C HL-60 cell Nitric Oxide |
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