| 速效醒脑滴丸的提取工艺研究 |
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| 引用本文： | 王玉蓉,吴清,王晓强,任天池. 速效醒脑滴丸的提取工艺研究[J]. 北京中医药大学学报, 2002, 25(5): 43-46. DOI: 10.3321/j.issn:1006-2157.2002.05.017 |
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| 作者姓名： | 王玉蓉 吴清 王晓强 任天池 |
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| 作者单位： | 北京中医药大学中药学院,北京,100102 |
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| 摘 要： | 探讨速效醒脑滴丸中川芎的提取工艺.采用渗漉法提取川芎中有效部位,用正交设计法对提取溶媒(乙醇)的浓度、用量及浸泡时间进行实验考察,以高效液相色谱(HPLC)法测定川芎主要有效成分阿魏酸、川芎嗪的含量,筛选出最佳提取工艺.结果表明用70%乙醇、浸泡24 h、溶媒量8倍的渗漉条件阿魏酸、川芎嗪的含量最高.
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| 关 键 词： | 速效醒脑滴丸 阿魏酸 川芎嗪 高效液相色谱法 |
| 修稿时间： | 2002-04-18 |
Study on the Technology for Preparing Suxiaoxingnao Gutta Pills |
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| Wang Yurong,Wu Qing,Wang Xiaoqiang,et al.. Study on the Technology for Preparing Suxiaoxingnao Gutta Pills[J]. Journal of Beijing University of Traditional Chinese Medicine, 2002, 25(5): 43-46. DOI: 10.3321/j.issn:1006-2157.2002.05.017 |
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| Authors: | Wang Yurong Wu Qing Wang Xiaoqiang et al. |
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| Abstract: | The technology of extracting the active components from Chuanxiong (the dried rhizome of Ligusticum chuanxiong) in preparing Suxiaoxingnao Gutta Pills was investigated. The technique of percolation was used to extract the active components from Chuanxiong; the concentration and the amount of the percolation solvent (alcohol) and the time for the immersion of Chuanxiong in the solvent were determined by the orthogonal design; and HPLC was used to determine the contents of ferulic acid and ligustrazine, the two main active components of Chuanxiong. The results showed that ferulic acid and ligustrazine in the extract could reach their highest concentrations when being extracted by percolation on condition that the 70% alcohol was used as percolation solvent, the time for the immersion of Chuanxiong was 24 hours, and the amount of percolation solvent was 8 times the amount of the crude drug. |
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| Keywords: | Suxiaoxingnao Gutta Pills Ferulic Acid Ligustrazine HPLC |
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