盐酸戊乙奎醚治疗急性有机磷农药中毒的临床研究 |
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引用本文: | 张建新.盐酸戊乙奎醚治疗急性有机磷农药中毒的临床研究[J].中国当代医药,2010,17(32):42-43. |
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作者姓名: | 张建新 |
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作者单位: | 新乡医学院第一附属医院急诊科,河南卫辉,453100 |
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摘 要: | 目的:观察盐酸戊乙奎醚(长托宁)在抢救急性有机磷农药中毒患者中的临床疗效。方法:将本院进行抢救的47例急性有机磷农药中毒患者作为观察组,给予盐酸戊乙奎醚联合氯解磷定治疗;既往本科应用传统的阿托品加氯解磷定进行抢救的47例急性有机磷中毒患者作为对照组,比较两组患者的临床疗效。结果:观察组的临床疗效、平均住院时间、CHE恢复时间、中毒症状消失时间及意识清醒时间与对照组比较,差异均有统计学意义(P〈0.05);并且不良反应的发生率仅为10.6%,明显比对照组少(P〈0.05)。结论:盐酸戊乙奎醚(长托宁)治疗急性有机磷农药中毒患者疗效确切,不良反应少,值得广泛应用。
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关 键 词: | 急性有机磷农药中毒 盐酸戊乙奎醚 氯解磷定 |
The clinical study of penehyclidine hydrochloride combined with pralidoxime chloride in treatment of acute organophosphate insecticides toxicosis |
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Authors: | ZHANG Jianxin |
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Institution: | ZHANG Jianxin (Department of Emergency,the First Affiliated Hospital of Xinxiang Medical College,He'nan Province,Weihui 453100,China) |
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Abstract: | Objective:To observe the penehyclidine hydrochloride (PHC) in treatment of patients with acute organophosphorus pesticide poisoning in the clinical efficacy.Methods:The hospital for emergency treatment of 47 cases of patients with acute organophosphorus pesticide poisoning as the observation group,given the joint penehyclidine hydrochloride pralidoxime chloride treatment;previous traditional undergraduate application of atropine to rescue the chlorination of 47 prali doxime cases of acute organophosphate poisoning as a control group of patients,the clinical efficacy of two groups were compared.Results:The clinical observation group,the average length of stay,CHE recovery time,poisoning symptoms time and conscious of time and the control group,the difference was statistically significant (P0.05);and the incidence rate of adverse reactions was 10.6%,significantly less than the control group (P0.05).Conclusion:Penehyclidine hydrochloride (PHC) in the treatment of patients with acute organophosphorus pesticide poisoning is effective and less adverse reaction,it is widely used. |
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Keywords: | Acute organophosphorus pesticide poisoning Penehyclidine hydrochloride Pralidoxime chloride |
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