强直性脊柱炎157例临床分析

本文对157例强直性脊柱炎患者进行了临床分析。认为AS多初发于15—24岁之间的男性青年,男女发病比例为14.7:1。有23.6％的病人有家族史。初发关节多在髋关节(33.1％)、腰椎(24.2％)及骶髂关节(21.7％);受累关节以骶髂关节及脊柱为主。对AS的诊断必须有经X线摄片证实的单侧或双侧骶髂关节炎,并有腰背部疼痛和僵硬,脊柱活动进行性障碍,胸扩度少于2.5cm及HLA—B_(27)阳性,RF阴性.

Clinical analysis of 157 cases of ankylosing spondylitis

The clinical pictures of ankylosing spondylitis ( AS)were analyzed in 157 patients. It was found that AS occurs more frequently between 15 to 30 years of age, being more prevalent in men than in women. The incidence ratio of male to female was 14.7:1. Approximately 23.6% of patients had a positive family history with the disease. The initial joint involvement was usually located in the hip ( 33.1%) , lumbar spine ( 24.2% ) and sacroiliac joints ( 21 .7% ) , and the spine and sacroiliac joints are predominatly affected. The definite diagnosis of AS requires X-Ray evidence of unilateral or bilateral sacroiliitis, presence of pain at the dorsolumbar junction or in the lumbar spine with stiffness, progressive limitation of motion of the spine, limitation of chest expansion to less than 2.5cm and HLA-B2v positive and rheumatoid factor ( RF ) negative.