静脉滴注拉贝洛尔治疗高血压急症的疗效和安全性

目的：评价静脉滴注拉贝洛尔治疗高血压急症的降压疗效及安全性。方法：31例高血压急症患者接受拉贝洛尔（1－4mg/min,iv gtt）治疗。结果：治疗前血压为23.2／16.5kPa，拉贝洛尔治疗2h后90％（28／31）患者平均血压下降15％－25％，治疗6h后血压控制在21.3／13.3kPa以下者为94％，拉贝洛尔降压起效快县无低血压现象发生。结论：静脉滴注拉贝洛尔治疗高血压急症有效、安全。

Efficacy and safety of intravenous labetalol in treatment of Chinese hypertension emergencies

AIM: To evaluate the efficacy in lowering blood pressure, and the safety of intravenous drip labetalol in the treatment of Chinese hypertension emergencies. METHODS: Thirty one Chinese patients with hypertension emergencies received intravenous labetalol (1-4 mg/min). RESULTS: Pretreatment blood pressure values were 23 2/16 5 kPa. Treatment response (15%-25% decrease in mean arterial pressure after 2 h treatment) was achieved in 90% (28/31) of labetalol treated patients. After 6 h treatment, 94% patients reached goal blood pressure (<21 3/13 3 kPa). The short response time to lower blood pressure and no hypotention were observed in labetalol treated patients. CONCLUSION: It is suggested that intravenous drip labetalol is highly effective and safe in the treatment of Chinese hypertension emergencies.