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铜绿假单胞菌注射液腔内注入治疗23例恶性心包积液的临床观察
引用本文:朱亚芳,魏金芝,顾洪兵.铜绿假单胞菌注射液腔内注入治疗23例恶性心包积液的临床观察[J].现代肿瘤医学,2011,19(12):2458-2459.
作者姓名:朱亚芳  魏金芝  顾洪兵
作者单位:南通市肿瘤医院内科,江苏,南通,226361
摘    要:目的:观察铜绿假单胞菌注射液(PA-MSHA)腔内注入治疗恶性心包积液的疗效及安全性。方法:对23例恶性心包积液患者,先心包腔内置入中心静脉导管行持续引流,待积液基本排尽后注入PA-MSHA 2-3ml和地塞米松5mg。夹闭引流管5-7天后复查B超,如效果不佳则再次引流后重复注射上述药物,反之则拔管。结果:共治疗23例,完全缓解14例(60.9%),部分缓解7例(30.4%),总有效率91.3%。心包腔内注药后有5例发热,2例胸痛。结论:PA-MSHA腔内注入治疗恶性心包积液疗效满意,不良反应不大。

关 键 词:恶性心包积液  铜绿假单胞菌  心包穿刺

Treatment of 23 cases of malignant hydropericardium with intracavitary administration of pseudomonas aeruginosa injection
ZHU Yafang,WEI Jinzhi,GU Hongbing.Treatment of 23 cases of malignant hydropericardium with intracavitary administration of pseudomonas aeruginosa injection[J].Journal of Modern Oncology,2011,19(12):2458-2459.
Authors:ZHU Yafang  WEI Jinzhi  GU Hongbing
Institution:ZHU Yafang,WEI Jinzhi,GU Hongbing Department of Medicine,Nantong Tumor Hospital,Jiangsu Nantong 226361,China
Abstract:Objective:To evaluate the efficacy of pseudomonas aeruginosa injection(PA-MSHA) in treatment of malignant hydrropericardium.Methods:Twenty-three patients with malignant hydropericardium were enrolled.After drairage of effusion by inserting central venous catheter into pericardial cavity,all patients were injected with 2-3ml of PA-MSHA and 5mg of dexamethasome.Ultrasound was performed to show pericardial exudates 5-7 days after injection of PA-MSHA.Patients who had a poor response after 5-7 days will have a ...
Keywords:malignant hydropericardium  pseudomonas aeruginosa agent  pericardial puncture  
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