| 吉西他滨联合奈达铂治疗老年晚期食管癌疗效观察 |
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| 引用本文： | 纪媛媛,李军扩,王俊生. 吉西他滨联合奈达铂治疗老年晚期食管癌疗效观察[J]. 现代肿瘤医学, 2011, 19(12): 2442-2443. DOI: 10.3969/j.issn.1672-4992.2011.12.24 |
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| 作者姓名： | 纪媛媛 李军扩 王俊生 |
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| 作者单位： | 安阳市肿瘤医院,河南,安阳,455000 |
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| 摘 要： | 目的:观察吉西他滨联合奈达铂治疗老年晚期食管癌的疗效及不良反应。方法:45例经病理学确诊为食管癌的患者,年龄均大于65岁,给予吉西他滨联合奈达铂化疗,21天为一周期,连用两周期后评价疗效及不良反应。结果:45例患者中CR 10例,PR 9例,SD 5例,PD 21例,总有效率RR为42.2%,中位生存时间9.6个月。结论:吉西他滨联合奈达铂治疗老年晚期食管癌疗效较好,不良反应轻,耐受性好,值得临床推广应用。
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| 关 键 词： | 吉西他滨 奈达铂 食管癌 化疗 |
Efficiency of combination chemotherapy with gemcitabine and nedaplatin in the treatment of old advanced esophageal cancer patients |
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| JI Yuanyuan,LI Junkuo,WANG Junsheng. Efficiency of combination chemotherapy with gemcitabine and nedaplatin in the treatment of old advanced esophageal cancer patients[J]. Journal of Modern Oncology, 2011, 19(12): 2442-2443. DOI: 10.3969/j.issn.1672-4992.2011.12.24 |
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| Authors: | JI Yuanyuan LI Junkuo WANG Junsheng |
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| Affiliation: | JI Yuanyuan,LI Junkuo,WANG Junsheng Anyang Tumour Hospital,Henan Anyang 455000,China |
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| Abstract: | Objective:To observe the efficiency and toxicity of combination chemotherapy with gemcitabine and nedaplatin in the treatment of old advanced esophageal cancer.Methods: Forty-five cases of advanced esophageal cancer,all were older than sixty-five,treated with gemcitabine and nedaplatin,the cycle was repeated every 21 days,after two consecutive treatment,the short term efficacy and adverse effects was observed.Results: Among the forty-five patients,ten patients were CR,nine patients PR,five SD,twenty-one PD,... |
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| Keywords: | gemcitibine nedaplatin esophageal cancer chemotherapy |
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