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广西侗族人群ABO及Rh血型分布调查分析
引用本文:焦伟,黎海澜,王晨,伍焕秀,莫柱宁,阳子骥,王巍华,刘斐,朱自严.广西侗族人群ABO及Rh血型分布调查分析[J].陕西医学杂志,2011,40(11):1531-1532.
作者姓名:焦伟  黎海澜  王晨  伍焕秀  莫柱宁  阳子骥  王巍华  刘斐  朱自严
作者单位:1. 广西壮族自治区人民医院输血科 南宁530021
2. 上海血液中心输血研究所
基金项目:广西科学研究与技术开发计划项目(桂科攻0993003B-26)
摘    要:目的:了解广西侗族人群ABO及Rh血型分布及基因频率。方法:对检测人群严格入选标准,随机抽取1927例非血缘关系的广西侗族人群进行ABO及Rh血型鉴定和分析。结果:ABO血型分布特征:O>B>A>AB;基因频率p(A)=0.1556、q(B)=0.1920、r(O)=0.6524;Rh(D)阴性率为0.052%,d基因频率0.0228。Rh发现8种表型,以CCDee频率最高(65.28%),未发现CCDEE表型。组合体基因频率以CDe(0.8080)为最高。结论:广西侗族人群ABO、Rh血型分布符合国内南方少数民族的分布特征,但Rh阴性比例明显低于汉族人群。

关 键 词:ABO血型系统  VRh-Hr血型系统  数据收集  少数民族  @广西地区

The investigation and analysis of ABO and Rh blood type distribution in Guangxi Dong nationality
Institution:Department of Blood Transfusion,the People's Hospital of Guangxi Zhuang Autonomous Region(Nanning 530021) Jiao Wei Li Hailan Wang Chen et al
Abstract:Objective:To survey ABO and Rh blood type distribution and gene frequency in Guangxi Dong nationality.Method:1,927 unrelated people of Guangxi Dong nationality were randomly collected and the ABO/Rh blood type were identified and analyzed.Result:The feature of ABO blood type distribution was: OBAAB;The gene frequency was p(A)=0.1556、q(B)=0.1920、r(O)=0.6524;Rh(D) negative rate was 0.052%,d gene frequency was 0.0228.Eight phenotypes were found in Rh blood type,CCDee frequency was highest(65.28%),CCDEE phenotype was not found.CDe(0.8080) was highest in the combination of gene frequency.Conclusion:The distribution of ABO and Rh blood type in Guangxi Dong nationality is accord with the feature of distribution in China southern minority nationalities,but Rh negative ratio is obviously lower than Han nationality.
Keywords:ABO blood-group system Hr-Hr blood-group system Data collection Minority group @Guang Xi area  
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