Non-functional parathyroid carcinoma: a case report and review of the literature |
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| Authors: | Liang Wang Dali Han Wanjun Chen Shuguang Zhang Zhiqi Wang Ke Li Yongsheng Gao Shujuan Zou Aiju Yang |
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| Affiliation: | 1.Department of Head and Neck Surgery; Shandong Cancer Hospital & Institute; Jinan, China;2.Department of Medicine and Life Sciences College of Shandong Academy of Medical Sciences; Jinan University; Jinan, China;3.Department of Radiation Oncology; Shandong Cancer Hospital & Institute; Jinan, China;4.Department of Pathology; Shandong Cancer Hospital & Institute; Jinan, China |
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| Abstract: | Non-functional parathyroid carcinoma is an exceedingly rare disease with 31 reported cases since 1909. Because of the scarce number of cases of non-functional parathyroid carcinoma, there are no evidence-based recommendations for its optimal treatment. Surgery, including en bloc resection of the carcinoma, ipsilateral thyroid lobe and isthmus together with a neck dissection only in case of lymph node involvement, is the main treatment for non-functioning parathyroid carcinoma. The patient usually has a poorer prognosis because of detection at advanced stages, the relative ineffectiveness of adjuvant treatment modalities and the lack of adequate parameters for clinical follow-up. In this report, we present a case of non-functional parathyroid carcinoma at our institution, and we review the previous literature to discuss the latest advances in the diagnosis and treatment of this rare disease. |
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| Keywords: | carcinoma non-functional parathyroid surgery |
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