The association between vitamin C dietary intake and its serum levels with anthropometric indices: A systematic review and meta-analysis |
| |
| Affiliation: | 1. Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran;2. Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran;3. Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran;4. Department of Nutrition, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran;5. Department of Clinical Nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran;1. Clinic for Complementary Medicine and Diet in Oncology, Local Health Unit Tuscany North West, Lucca, Italy;2. Center for Acupuncture and Traditional Chinese Medicine, Local Health Unit Central Tuscany, Firenze, Italy;3. Integrative Medicine Center, CERFIT, University Hospital of Careggi Hospital, Firenze, Italy;4. Center for Integrative Medicine, Hospital of Pitigliano, Local Health Unit South East Tuscany, Grosseto, Italy;5. Tuscan Regional Center for Integrative Medicine, Firenze, Italy;6. Breast Unit, AOUP, University Hospital of Pisa, Italy;7. Oncology Department, Local Health Unit Central Tuscany, Italy;8. Oncology Department, Local Health Unit Tuscany North West, Carrara, Italy;9. Oncology Department, Local Health Unit South East Tuscany, Arezzo, Italy;10. Coordinator for the Tuscan Oncology Network, University Hospital of Careggi, Firenze, Italy;1. School of Physical Education and Health, Shanghai Lixin University of Accounting and Finance, Shanghai, China;2. Physical Education Department, Shanghai University of Finance and Economics, Shanghai, China;1. Body-Brain-Mind Laboratory, School of Psychology, Shenzhen University, Shenzhen, 518060, China;2. Research Group Degenerative and Chronic Diseases, Movement, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany;3. School of Rehabilitation, Sport and Psychology, AECC University College, UK;1. Australian Research Centre in Complementary and Integrative Medicine, Faculty of Health, University of Technology Sydney, Ultimo, Australia;2. School of Social Science, University of Queensland, Brisbane, Australia;3. National Centre of Naturopathic Medicine, Southern Cross University, Lismore, Australia;1. Department of Traditional Medicine, Institute for Studies in Medical History, Persian and Complementary Medicine, School of Persian Medicine, Iran University of Medical Sciences, Tehran, Iran;2. Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran |
| |
| Abstract: | Backgroundstudies showed inflammatory background of overweight and obesity. Prevalence of weight disorders has dramatically increased over the past few decades. Vitamin C is an antioxidant and may be associated with weight disorders. This study aims to systematically review the relationship between dietary and serum vitamin C levels with anthropometric indices.MethodsA systematic search was conducted in Medline database (PubMed), Scopus, Embase, Web of Science, Cochrane library and Google Scholar up to the end of August 2021. All observational studies that assessed the relationship between dietary or circulating vitamin C levels and body mass index (BMI) and waist circumference (WC) on adults were included. The quality of included studies was assessed using the National Institute of Health quality assessment tool.ResultsAmong 11,689 studies, 47 and 37 articles were included in the systematic review and meta-analysis, respectively. There was an inverse significant correlation between WC and serum vitamin C levels (r = −0.28, 95% CI: −0.35,-0.21, I2 = 14.2%) and between BMI and serum vitamin C levels (r = −0.17, 95% CI: −0.25, −0.09, I2 = 72.8%). Higher vitamin C consumption was significantly associated with lower BMI. There were no significant differences in serum vitamin C levels between normal-weight and overweight subjects, but serum vitamin C levels were significantly higher in obese subjects in comparison with normal-weight subjects.ConclusionResults showed that both dietary and serum vitamin C levels were inversely associated with BMI and WC. More well-designed clinical trials are needed to assess the effect of vitamin C supplementation in prevention and treatment of obesity. |
| |
| Keywords: | Ascorbic acid Waist circumference Body Mass Index Anthropometry Meta-analysis |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
