重症监护室长期机械通气治疗患者便秘发生危险因素分析

目的分析重症监护室(ICU)长期机械通气治疗患者便秘发生危险因素。方法选取2016年2月-2019年3月达州市中西医结合医院收治的行ICU机械通气治疗时间超过14 d的患者100例进行研究,根据患者治疗期间是否发生便秘分为便秘组44例和非便秘组56例。收集2组患者一般临床资料和可疑危险因素,分析ICU长期机械通气治疗患者便秘发生危险因素。结果单因素分析得出,年龄、应用抗生素、应用镇静剂、口服钾剂、鼻饲液种类、鼻饲每天喂养量、鼻饲喂养速度在便秘组和非便秘组患者中比较差异有统计学意义(P<0.05);多因素分析得出,年龄(OR=2.332,P=0.000)、应用镇静剂(OR=2.544,P=0.002)、鼻饲液种类(OR=5.164,P=0.000)、鼻饲每天喂养量(OR=2.614,P=0.004)、鼻饲喂养速度(OR=1.645,P=0.002)为影响ICU长期机械通气治疗患者便秘发生独立危险因素。结论影响ICU长期机械通气治疗患者便秘发生危险因素较多,临床上针对性实施预防干预对降低便秘发生风险有重要价值。

Analysis of risk factors of constipation in intensive care unit patients treated with long-term mechanical ventilation

Objective Analyse of the risk factors for constipation in patients with intensive care unit(ICU)long-term mechanical ventilation.Methods Select 100 case of ICU mechanical ventilation treatment for more than 14 d patients in Dazhou integrated traditional Chinese and Western Medicine hospital form February 2016 to March 2019 as studying object.According to whether constipation occurred during the treatment of patients,it was divided into 44 cases of constipation group and 56 cases of non-constipation group.The general clinical data and suspicious risk factors of the two groups of patients were collectedto explore the risk factors of constipation in patients with long-term mechanical ventilation.Results Univariate analysis showed that age,application of antibiotics,application of sedatives,oral potassium,nasal feeding,daily feeding of nasal feeding,and feeding rate of nasal feeding were statistically significant in patients with constipation and non-constipation(P<0.05).Multivariate analysis showed age(OR=2.332,P=0.000),sedative(OR=2.544,P=0.002),nasal feeding(OR=5.164,P=0.000),daily feeding of nasal feeding(OR=2.614,P=0.004),nasal feeding speed(OR=1.645,P=0.002)were all independent risk factors for constipation in patients with long-term mechanical ventilation in ICU.Conclusion There are many risk factors for constipation in patients with long-term mechanical ventilation in ICU.Targeted prevention intervention in clinical practice is of great value in reducing the risk of constipation.