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Comparison of the systematic Inflammatory response syndrome and the quick sequential organ failure assessment for prognostic accuracy in detecting sepsis in the emergency department: A systematic review |
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| Institution: | 1. Lovisenberg Diaconal University College, Department for postgraduate studies, Oslo, Norway;2. Emergency Medicine section Bærum Hospital, Norway;3. Lovisenberg Diaconal University College, Department for postgraduate studies, Oslo, Norway;4. Lovisenberg Diaconal University College, Department for postgraduate studies, Oslo, Norway;5. Intensive Care Nurse Specialist, Master of Nursing Sci., PhD. Lovisenberg Diaconal University College, Department for postgraduate studies, Oslo, Norway |
| Abstract: | BackgroundAwareness and prompt recognition of sepsis are essential for nurses working in the emergency department (ED), enabling them to make an initial assessment of patients and then to sort them according to their condition s severity. The aim of this systematic review was to investigate prognostic accuracy in detecting sepsis in the emergency department by comparing the previous sepsis-2 screening tool, the Systemic Inflammatory Response Syndrome (SIRS) and the current sepsis-3 screening tool, the Quick Sequential Organ Failure Assessment (qSOFA).MethodsThis systematic review used the guideline by Bettany-Saltikov and McSherry and was reported according to the Preferred Reporting Items for Systematic Reviews and meta-Analyses (PRISMA) 2020 checklist. The protocol was registered in PROSPERO. A systematic search was conducted using the CINAHL, EMBASE and MEDLINE databases. Study selection and risk of bias was performed independently by pair of authors.ResultsFive articles were included. Overall, SIRS showed higher sensitivity than qSOFA, while qSOFA showed higher specificity than SIRS. The positive predictive value for qSOFA was superior, while there was a minor deviation in negative predictive value between qSOFA and SIRS.ConclusionThe overall recommendation based on the included studies indicates that qSOFA is the better-suited screening tool for prognostic accuracy in detecting sepsis in the emergency department. |
| Keywords: | Emergency department Predictive value Prognostic accuracy qSOFA Sensitivity Sepsis SIRS Specificity Systematic review CASP"} {"#name":"keyword" "$":{"id":"k0055"} "$$":[{"#name":"text" "_":"Critical Appraisal Skills Programme CI"} {"#name":"keyword" "$":{"id":"k0065"} "$$":[{"#name":"text" "_":"Confidence interval ED"} {"#name":"keyword" "$":{"id":"k0075"} "$$":[{"#name":"text" "_":"Emergency Department ESI"} {"#name":"keyword" "$":{"id":"k0085"} "$$":[{"#name":"text" "_":"Emergency Severity Index GCS"} {"#name":"keyword" "$":{"id":"k0095"} "$$":[{"#name":"text" "_":"Glasgow Coma Scale ICU"} {"#name":"keyword" "$":{"id":"k0105"} "$$":[{"#name":"text" "_":"Intensive Care Unit kPa"} {"#name":"keyword" "$":{"id":"k0115"} "$$":[{"#name":"text" "_":"Kilopascal mmHg"} {"#name":"keyword" "$":{"id":"k0125"} "$$":[{"#name":"text" "_":"Millimeter of mercury MAP"} {"#name":"keyword" "$":{"id":"k0135"} "$$":[{"#name":"text" "_":"mean arterial pressure (MAP) NPV"} {"#name":"keyword" "$":{"id":"k0145"} "$$":[{"#name":"text" "_":"Negative Predictive Value PaCO2"} {"#name":"keyword" "$":{"id":"k0155"} "$$":[{"#name":"text" "_":"arterial partial pressure of carbon dioxide PICO"} {"#name":"keyword" "$":{"id":"k0165"} "$$":[{"#name":"text" "_":"Patient intervention Comparison Outcome PPV"} {"#name":"keyword" "$":{"id":"k0175"} "$$":[{"#name":"text" "_":"Positive Predictive Value PV"} {"#name":"keyword" "$":{"id":"k0185"} "$$":[{"#name":"text" "_":"Predictive Value qSOFA"} {"#name":"keyword" "$":{"id":"k0195"} "$$":[{"#name":"text" "_":"quick sequential organ failure assessment SD"} {"#name":"keyword" "$":{"id":"k0205"} "$$":[{"#name":"text" "_":"Standard Deviation SIRS"} {"#name":"keyword" "$":{"id":"k0215"} "$$":[{"#name":"text" "_":"Systemic Inflammatory response syndrome SOFA"} {"#name":"keyword" "$":{"id":"k0225"} "$$":[{"#name":"text" "_":"sequential Organ Failure Assessment |
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