A prospective single-center study evaluating the efficacy of the stomach,intestinal, and pylorus-sparing procedure |
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| Affiliation: | 1. Department of Surgery, Hartford Hospital/HealthCare, Hartford, Connecticut;2. Department of Research, Hartford Hospital/HealthCare, Hartford, Connecticut;3. Department of Nutritional Sciences, Howard University, Washington, District of Columbia;4. Department of Kinesiology, University of Connecticut, Storrs, Connecticut;5. Institute for Collaboration on Health, Intervention, and Policy, University of Connecticut, Storrs, Connecticut;6. Wesleyan Library, Wesleyan University, Middletown, Connecticut;7. Department of Nursing, University of Québec en Outaouais, Gatineau, Quebec, Canada;8. Institut du Savoir Montfort-Recherche, Ottawa, Ontario, Canada;1. Urology Department, Rijnstate Hospital, Arnhem, the Netherlands;2. Bariatric Surgery Department, Rijnstate Hospital, Arnhem, the Netherlands;3. Internal Medicine Department, Rijnstate Hospital, Arnhem, the Netherlands;1. Department of General Surgery, Bariatric and Metabolic Institute, Cleveland Clinic, Cleveland, Ohio;2. Department of Clinical Transformation, Cleveland Clinic, Cleveland, Ohio;1. Sam Houston State University College of Osteopathic Medicine, Conroe, Texas;2. Department of Psychiatry, Program for Obesity, Weight, and Eating Research, Yale University School of Medicine, New Haven, Connecticut;3. Department of General Surgery, Bellevue Hospital/NYU Langone Health, New York, New York |
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| Abstract: | BackgroundThe stomach, intestinal, and pylorus-sparing (SIPS) procedure is a single-anastomosis duodeno-intestinal bypass used in obesity management.ObjectiveWeight and metabolic outcomes in patients with severe obesity who underwent the SIPS procedure were evaluated in a community hospital–based study.SettingCommunity hospital.MethodsThis single-site prospective study of patients who underwent the SIPS procedure evaluated outcomes at 12 and 24 months. Mean changes in total weight loss and body mass index (BMI) and resolution of gastroesophageal reflux disease (GERD), obstructive sleep apnea (OSA), hypertension, type 2 diabetes (T2D), and hyperlipidemia were evaluated.ResultsAt baseline, 185 patients were enrolled; mean weight and BMI were 144.0 kg and 52.2 kg/m2, respectively. Data for 88 (47.6%) and 29 (15.7%) patients who completed follow-up at 12 and 24 months, respectively, were available. At 12 months, mean total weight loss was 35.6% (weight reduction of 51.3 kg) and BMI reduction of 17.8 points were achieved and were maintained for the 29 patients who completed 24-month follow-up. No leaks or infections occurred. Complications occurred in 8 patients (.4%) and were not serious. Resolution of GERD, OSA, hypertension, T2D, and hyperlipidemia achieved in 87.1%, 59.2%, 32.7%, 93.1%, and 87.6% of patients, respectively, at 12 months was maintained at 24 months. Nutritional deficiency was absent.ConclusionsPatients who underwent the SIPS procedure had meaningful reductions in weight and BMI, and many had resolution of metabolic co-morbidities; procedural complication rates were low. Our results support that the SIPS procedure is a safe and effective primary treatment for clinically severe obesity in a community-based hospital setting. |
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| Keywords: | Single-anastomosis duodeno-ileostomy (SADI) Stomach intestinal pylorus-sparing (SIPS) Loop duodenal switch Severe obesity Co-morbidity resolution |
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