| 循环肿瘤细胞在胃癌中应用的研究进展 |
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| 引用本文： | 王刘星,王黔. 循环肿瘤细胞在胃癌中应用的研究进展[J]. 安徽医药, 2023, 27(9): 1736-1740 |
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| 作者姓名： | 王刘星 王黔 |
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| 作者单位： | 贵州医科大学外科学教研室,贵州贵阳 550000;贵州医科大学外科学教研室,贵州贵阳 550000;贵州医科大学附属医院胃肠外科,贵州贵阳 550000 |
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| 摘 要： | 复发和转移是导致胃癌术后低生存率的主要原因。循环肿瘤细胞在胃癌转移中的起到关键作用,所谓的“肿瘤细胞播散的上皮 -间质 /间质 -上皮假说”很好地解释了这一点。近年来,随着循环肿瘤细胞检测技术的进步,循环肿瘤细胞作为推动精准医学的重要技术得到了广泛的关注。该研究就循环肿瘤细胞在胃癌的早期诊断、治疗过程中的动态监测、预后的判断、个体化治疗中的研究进展及展望作一综述。
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| 关 键 词： | 胃肿瘤 循环肿瘤细胞 精准医学 液体活检 预后 |
Research progress in the application of circulating tumor cells in gastric cancer |
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| WANG Liuxing,WANG Qian. Research progress in the application of circulating tumor cells in gastric cancer[J]. Anhui Medical and Pharmaceutical Journal, 2023, 27(9): 1736-1740 |
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| Authors: | WANG Liuxing WANG Qian |
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| Affiliation: | Department of Surgery, Guizhou Medical University, Guiyang, Guizhou 550000, China; Department of Surgery, Guizhou Medical University, Guiyang, Guizhou 550000, China;Department of Gastrointestinal Surgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550000, China |
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| Abstract: | Recurrence and metastasis are the main reasons for the low survival rate of gastric cancer after operation. Circulating tu-mor cells play a key role in gastric cancer metastasis, which is well explained by the so-called "epithelial-mesenchymal /mesenchymalepithelial hypothesis of tumor cell dissemination". In recent years, with the progress of circulating tumor cell detection technology, cir-culating tumor cells, as an important technology to promote precision medicine, have attracted extensive attention. This study reviewsthe research progress and prospect of circulating tumor cells in early diagnosis, dynamic monitoring, prognosis and individualized treat-ment of gastric cancer. |
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| Keywords: | Stomach neoplasms Circulating tumor cell Precision medicine Liquid biopsy Prognosis |
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