Estimation of arterial compliance in aortic regurgitation: three methods evaluated in pigs |
| |
Authors: | S A Slørdahl H Piene J E Solbakken O Rossvoll S O Samstad B A J Angelsen |
| |
Institution: | (1) Department of Biomedical Engineering, University of Trondheim, 7006 Trondheim, Norway |
| |
Abstract: | Three methods for measuring arterial compliance when aortic regurgitation is present are examined. The first two methods are
based on a Windkessel model composed of two elements, compliance C and resistance R. Arterial compliance was estimated from
diastolic pressure waveforms and diastolic regurgitant flow for one method, and from systolic aortic pressure waveforms and
systolic flow for the other method. The third method was based on a three-element Windkessel model, composed of characteristic
resistance r, compliance C and resistance R. In this method arterial compliance was calculated by adjusting the model to the
modulus and phase of the first harmonic term of the aortic input impedance. The three methods were compared and validated
in six anaesthetised pigs over a broad range of aortic pressures. The three methods were found to give quantitatively similar
estimates of arterial compliance at mean aortic pressures above 60 mm Hg. Below 60 mm Hg, estimates of arterial compliance
varied widely, probably because of poor validity of the Windkessel models in the low pressure range. |
| |
Keywords: | Aortic regurgitation Arterial compliance Fourier analysis Impedance Mean aortic pressure Peripheral resistance Windkessel model |
本文献已被 SpringerLink 等数据库收录! |