从中医学视角探讨慢性胃炎“炎癌转化”过程的免疫失衡与重建

阴阳消长、邪正盛衰是中医学阐释疾病发生发展规律的重要理论基础,对于认识慢性胃炎"炎癌转化"过程及防治具有重要指导意义。现代医学认为免疫系统失衡是肿瘤发生的根本原因,而免疫治疗被誉为是人类最有希望攻克癌症的手段。中医学的阴阳、正邪学说与现代医学对免疫的认识具有很多相通之处,尤其是近年来提出肿瘤免疫治疗应从"免疫增强疗法"向"免疫正常化疗法"回归的理念,与中医学"调和阴阳,扶正祛邪"以恢复人体相对平衡状态的核心思想相一致。本文在中西医理论相辅相成、相互渗透、相互促进的基础上展开论述,旨在促进祖国传统医学与现代医学在慢性胃炎"炎癌转化"发展过程及防治策略上的理论融合与发展。

Destruction and reconstruction of immune balance in "inflammation to cancer" of chronic gastritis from the perspective of traditional Chinese medicine

The growth and decline of yin and yang, and the conflict between healthy qi and pathogenic factor are important theoretical foundations for traditional Chinese medicine(TCM) to interpret disease occurrence and development, which is of significance for guiding the understanding of "inflammation to cancer" of chronic gastritis and its prevention and treatment. From the perspective of Western medicine, the imbalance of the immune system is the root cause of tumors, and immunotherapy is hailed as the most promising means for curing cancer. The theories of yin and yang, and healthy qi and pathogenic factor of TCM have much in common with the understanding of immunity in western medicine. Especially in recent years, the idea that tumor immunotherapy should return from "immune enhancement" to "immune normalization" is similar to the core idea of "harmonizing yin and yang, reinforcing healthy qi to dispel pathogenic qi" in TCM. Based on the combination of theories from both traditional Chinese medicine and Western medicine, this paper aims to promote the theoretical integration and development of traditional Chinese medicine and Western medicine in prevention and treatment of "inflammation to cancer" of chronic gastritis.