经皮内窥镜下腰椎椎间盘切除术与显微内窥镜下椎间盘切除术治疗腰椎椎间盘突出症的荟萃分析

目的 系统分析并比较经皮内窥镜下腰椎椎间盘切除术(PELD)与显微内窥镜下椎间盘切除术(MED)治疗腰椎椎间盘突出症(LDH)的疗效.方法 利用中国知网、万方数据、维普网、中国生物医学数据库、PubMed、Embase、Cochrane Library、Ovid等数据库,检索国内外公开发表的治疗单节段LDH的中英文文献...

Percutaneous endoscopic lumbar discectomy versus micro endoscopic discectomy for lumbar disc herniation: a meta-analysis

Objective To systematically analyze and compare the effectiveness between percutaneous endoscopic lumbar discectomy(PELD)and micro endoscopic discectomy(MED)in the treatment of lumbar disc herniation(LDH).Methods CNKI,Wanfang Database,VIP,China Biological Medicine Database,PubMed,Embase,Cochrane Library and Ovid were searched for the articles in the treatment of single-segmental LDH published from the building of data base to November 20,2019.Prospective randomized controlled trials of PELD and MED in the treatment of LDH were collected.The eligible trials were extracted according to the inclusion and exclusion criteria.The RevMen 5.3 software was used for meta analysis.Results A total of 10 trials involving 956 patients were included,523 male and 433 female,455 PELD cases and 501 MED cases were enrolled.The results of meta-analysis showed that there were no significant differences in the mean operation time,visual analogue scale(VAS)score of postoperative low back pain and leg pain,the Oswestry disability index(ODI),the postoperative complication rate and re-operation rate.When compared with MED,PELD entailed shorter length of incision,in-bed time after operation and hospital stay,and higher radiation exposure,all with a significant difference(P<0.05).Conclusion PELD and MED are both effective and safe treatments for LDH.Compared to MED,PELD is more minimally invasive with shorter length of incision,in-bed time and hospital stay,but increases risk of intraoperative radiation exposure.