米索前列醇用于人工流产扩张宫颈的临床观察

目的探讨米索前列醇在人工流产术（妊娠7～11周）前应用的临床效果。方法采用术前12h口服米索前列醇0.4mg的方法，观察术时宫颈口扩张大小、出血量、手术时间以及人工流产综合征的发生率。结果术前口服米索前列醇可以使宫口松弛，子宫收缩良好，出血量减少，平均手术时间短，人工流产综合征发病率低，术后随访显示患者阴道流血时间短。结论口服米索前列醇简便、安全、有效，可以作为人工流产术前常规用药。

Observation on application of misoprostol in cervical dilatation for induced abortion

Objective To observe the clinical effect of applying misoprostol in cervical dilatation for induced abortion. Methods To study the clinical effect of misoprostol for induced abortion （ with gestation of 7 - 11weeks）. Misoprostol 0.4mg was orally taken by pregnant women at 12 hours before the operation, The cervical size, amount of blood loss, operation time, uterine contraction, and incidence of induced abortion syndrome were observed. Results The oral administration of misoprostol before operation has the effect on relaxation of cervix, promoting uterine contraction, reducing blood loss, shortening the operation lime, decreasing the incidence of induced abortion syndrome and shortening the bleeding time of vagina at the follow - up period after operation. Conclusions The oral administration of misoprostol is simple, safe and effective, so it can be used as routine medication before operation of induced abortion.