| 2型糖尿病视网膜病变患者同型半胱氨酸和胱抑素C水平的变化及相关性研究 |
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| 引用本文： | 张兰春.2型糖尿病视网膜病变患者同型半胱氨酸和胱抑素C水平的变化及相关性研究[J].山东医学高等专科学校学报,2011,33(3):165-169. |
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| 作者姓名： | 张兰春 |
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| 作者单位： | 临沭县人民医院,山东临沭,276700 |
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| 摘 要： | 目的探讨同型半胱氨酸(Hcy)与胱抑素C(Cystatin C)及超敏C反应蛋白(hs-CRP)与2型糖尿病视网膜病变(DR)的相关性。方法选择诊断为2型糖尿病患者无视网膜病变(NDR)组45例,背景期DR(BDR)组42例,增殖期DR(PDR)组46例,同时选择40例健康正常人做对照组。空腹血糖(FPG)采用葡萄糖氧化酶法,Hcy、Cystatin C采用酶联免疫分析法,hs-CRP采用免疫比浊法进行检测。结果糖尿病患者各组FPG、Hcy、Cystatin C、hs-CRP水平有随病情进展而增高的趋势(P<0.05或0.01),PDR组均高于对照组(P<0.05);Hcy与Cystatin C呈正相关(r=0.756,P<0.01)。结论 Hcy、Cystatin C、hs-CRP与DR的进程密切相关。
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| 关 键 词： | 同型半胱氨酸 胱抑素C 超敏C反应蛋白 2型糖尿病视网膜病变 |
THE CONTENTS CHANGES OF HCA AND CYSTATIN C IN PATIENTS WITH TYPE 2 DIABETIC RETINOPATHY |
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| ZHANG Lan-chun.THE CONTENTS CHANGES OF HCA AND CYSTATIN C IN PATIENTS WITH TYPE 2 DIABETIC RETINOPATHY[J].Journal of Shandong Medical College,2011,33(3):165-169. |
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| Authors: | ZHANG Lan-chun |
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| Affiliation: | ZHANG Lan-chun(Linshu County People's Hospital,Linyi,China 276700) |
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| Abstract: | Objective To investigate the changes of homocysteic acid(HCA),cystatin C and high-sensitivity C-reactive protein(hs-CRP) in patients with type 2 diabetic retinopathy(DR) and determine if any correlations exist among these factors.Methods The group of patients with type 2 diabetes mellitus(DM) without DR included 45 individuals,the group of Type 2 DM with nonproliferative DR consisted of 42 patients and the group of type 2 DM with proliferative DR was composed of 46 patients.The control group comprised 40 he... |
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| Keywords: | HCA Cystatin C hs-CRP Type 2 diabetic retinopathy |
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