手术治疗非小细胞肺癌152例临床分析

目的探讨手术治疗非小细胞肺癌的效果及影响预后的因素。方法回顾性分析1990年1月至2000年1月接受手术治疗的152例非小细胞肺癌患者的临床资料,并进行随访,采用Kaplan-Meier法计算5年生存率。结果5年总体生存率为36.8%,年龄、性别及术后是否化疗与预后无关,不同病理类型、病理分期和不同手术方式的5年生存率比较差异均有统计学意义(P<0.05)。结论手术是治疗非小细胞肺癌的首选方案。病理类型、病理分期和手术方式是影响预后的主要因素。早期诊断、早期手术治疗及选择合适的手术方式可改善预后。

Clinical analysis of surgical treatment of primary non-small cell lung cancer:a report of 152 cases

Objective To discuss therapeutic effect of surgery treatment of primary non-small cell lung cancer and relative factors of influencing prognosis.Methods A retrospective analysis was performed for clinical data of 152 patients with primary non-small cell lung cancer underwent operation in the fourth hospital of Jilin university between Jan.1990 and Jan.2000,and follow-up was made.5-year survival rate was calculated by Kaplan-Meier method.Results Overall 5-year survival rate was 36.8%.There was no significant relationships between age,sex,postoperative chemotherapy and prognosis(all P>0.05).There were significant relationships between pathological type,pathological stage,surgery mode and prognosis(all P<0.05).Conclusions Operation is the primary treatment for non-small cell lung cancer.Pathological type,pathological stage and surgery mode are important prognostic factors for non-small cell lung cancer.