Insulin-producing cells derived from stem/progenitor cells: therapeutic implications for diabetes mellitus |
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Authors: | Yuichi Hori |
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Institution: | (1) Development & Stem Cell Laboratory, Diabetes Research Institute University of Miami, Miami, FL 33136, USA |
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Abstract: | One of the most common diseases of the pancreas is diabetes mellitus. The current treatment of exogenous insulin supply is
not fully capable of achieving tight control of glucose regulation, leading to long-term complications. Hence, recent success
in islet transplantation-based therapies for diabetes mellitus and the extreme shortage of pancreatic islets have motivated
recent efforts to develop renewable sources of islet-replacement tissue. Of clinical interest, I review the recent progress
on stem cell-based strategies for diabetes in view of regenerative medicine. |
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