| 特非它唑的合成 |
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| 引用本文： | 罗成,朱少璇,彭锋. 特非它唑的合成[J]. 华西药学杂志, 2003, 18(5): 346-347 |
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| 作者姓名： | 罗成 朱少璇 彭锋 |
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| 作者单位： | 广州市医药工业研究所,广东,广州,510240 |
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| 摘 要： | 从中间体4-(4-溴丁酰基)苯基-a，a-二甲基乙氰开始，经缩合、还原、环化三步合成特非它唑，收率11％。
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| 关 键 词： | 特非它唑 合成 抗组胺药 药物开发 |
| 文章编号： | 1006-0103(2003)05-0346-02 |
| 修稿时间： | 2003-02-01 |
Synthesis of terfetrazole |
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| LUO Cheng,ZHU Shao-xuan,PENG Feng Guangzhou Pharmaceutical Industrial Research Institute,Guangzhou ,China. Synthesis of terfetrazole[J]. West China Journal of Pharmaceutical Sciences, 2003, 18(5): 346-347 |
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| Authors: | LUO Cheng ZHU Shao-xuan PENG Feng Guangzhou Pharmaceutical Industrial Research Institute Guangzhou China |
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| Affiliation: | LUO Cheng,ZHU Shao-xuan,PENG Feng Guangzhou Pharmaceutical Industrial Research Institute,Guangzhou 510240,China |
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| Abstract: | Terfetrazole was prepared from new intermedium 4-(4-bromobutyryl)-phenyl- a,a-Dimethylacetonitrile by condensation,reduction and cyclization with an overall yield of 11%. |
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| Keywords: | Terfetrazole Antihistamines drugs Synthesis |
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