Clinical Characteristics of 42 SARS Patients and Their Treatment of Integrative Chinese and Western Medicine |
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作者姓名: | Zou Jin-pan Hua Bao-jin Chen Chang-huai Xu Gui-cheng Su Hao Wang Yin Li Guang-xi Yang Zong-yan He Xia-xiu Liu Xi-ming Ni Qing Li Hui Zhao Hong Zhang Li-n Wang Wei-dong |
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作者单位: | Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053,Guang'anmen Hospital,China Academy of TCM,Beijing 100053 |
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摘 要: | Objictive:To understand the clinical manifestation of severe acute respiratory syndrome(SARS)and explore its effective treatment with integrative Chinese and western medicine(ICWM).Methods:The data of patients,whose diagnosis of SARS had been confirmed were summarized and ana-lyzed,and clinical observation was conducted when the patients were treated with ICWM.Results:In theearly stage of the 42 patients,the symptoms revealed were fever in 100% of SARS patients,headache in92.9%,aversion to cold in 76.2%,chest stuffiness in 76.2%,cough in 73.8%and myalgia in 88.1%;Pulmonary lesion Involves ≥3 lobes in 42.9%,2 lobes in 47.6% and 1 lobe in 9.5%;61.9% of themshowed liver function abnormality(increase of ALT or AST),47.6% showed elevated myocardial enzyme(CK or CK-MB),0.48% showed an inclination of renal function(higher of BUN or Cr);in their T lym-Phocyte subsets,91.2%(31/34 Patients)had lowered CD_3 and 76.5%(26/34 Patients)lowered CD_4/CD_8ratio.In the mid-late stage,the symptoms were lass
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收稿时间: | 4 June 2003 |
Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine |
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Authors: | Zou Jin-pan Hua Bao-jin Chen Chang-huai Xu Gui-cheng Su Hao Wang Yin Li Guang-xi Yang Zong-yan He Xia-xiu Liu Xi-ming Ni Qing Li Hui Zhao Hong Zhang Li-na and Wang Wei-dong |
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Abstract: | Objective: To understand the clinical manifestation of severe acute respiratory syndrome (SARS) and explore its effective treatment
with integrative Chinese and western medicine (ICWM).Methods: The data of patients, whose diagnosis of SARS had been confirmed were summarized and analyzed, and clinical observation
was conducted when the patients were treated with ICWM.Results: In the early stage of the 42 patients, the symptoms revealed were fever in 100% of SARS patients, headache in 92. 9%, aversion
to cold in 76. 2%, chest stuffiness in 76. 2%, cough in 73. 8% and myalgia in 88. 1%; pulmonary lesion involves ≥3 lobes in
42. 9%, 2 lobes in 47. 6% and 1 lobe in 9. 5%; 61. 9% of them showed liver function abnormality (increase of ALT or AST),
47. 6% showed elevated myocardial enzyme (CK or CK-MB), 0. 48% showed an inclination of renal function (higher of BUN or Cr);
in their T lymphocyte subsets, 91. 2% (31/34 patients) had lowered CD3 and 76. 5% (26/34 patients) lowered CD4/CD8 ratio. In the mid-late stage, the symptoms were lassitude and weakness in 85. 7%, scare in 81. 0%, short of breath or chest
stuffiness in 71. 4%, loss of appetite in 64. 3%; light dark tongue proper in 52.4%, yellow and white tongue coating in 45.
2%, and yellow thick coating on the middle-root part of the tongue in 21. 4%. Most of them were asymptomatic when discharged
from hospital, with 92. 8% of their pulmonary lesion, according to chest film, completely absorbed and liver function, myocardial
enzyme and renal function all normalized. However, of the 30 patients who had CD3 reexamination, 70% of the CD3 showed lower than normal range and 36. 7% showed their CD4/CD8 inclined to lower margin, follow-up should be done for these patients. Of the 42 patients, who received western medicine
(WM) alone in the early stage and ICWM in the mid-late stage, 10 were severe cases and 3 critical cases, but none of them
died. The mean defervescent time was 3. 52±0. 85 days, the time for complete absorption of pulmonary lesion judged by chest
X-ray film was 26. 82±5. 98 days, and the mean hospitalization time was 33. 60±4. 37 days.Conclusion: The manifestation of SARS is multifarious, showing that there were damage in multiple organs. The T lymphocyte count percentage
and its subsets, CD3 and CD4 /CD8 ratio, are valuable for early diagnosis and follow-up in the rehabilitation stage. Majority of the patients could be clinically
cured. Combined treatment of WM and TCM according to syndrome differentiation and psychiatric intervention are beneficial
to remit partial symptoms and promote rehabilitation. |
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Keywords: | severe acute respiratory syndrome clinical characteristics integrative Chinese and western medical treatment |
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