| 多指标综合评分法优选补正续骨颗粒最佳提取工艺 |
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| 引用本文： | 田原,樊晖,关雪峰,张锡玮,孙科峰.多指标综合评分法优选补正续骨颗粒最佳提取工艺[J].长春中医药大学学报,2015(6):1134-1136. |
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| 作者姓名： | 田原 樊晖 关雪峰 张锡玮 孙科峰 |
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| 作者单位： | 辽宁中医药大学附属医院,沈阳,110032 |
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| 基金项目： | 辽宁省科学技术计划项目，辽宁中医药大学 |
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| 摘 要： | 目的：优选补正续骨颗粒的提取工艺。方法采用 L9（34）正交试验法，以出膏率为考察指标，优选最佳水提取工艺，以川续断皂苷Ⅵ与柚皮苷总含量及出膏率综合评分为评价指标，优选最佳乙醇提取工艺。结果最佳水提取工艺为加6倍量水，提取2次，每次提取1 h。最佳乙醇提取工艺为加6倍量60％乙醇，提取3次，每次2 h。结论优选的提工艺稳定可行，适用于补正续骨颗粒的工业化生产。
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| 关 键 词： | 补正续骨颗粒 川续断皂苷Ⅵ 柚皮苷 正交试验 |
optimization of extraction technology for Buzheng Xugu granules by multi-index comprehensive evaluation method |
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| Abstract: | objective To optimize extraction technology of Buzheng Xugu granules. Methods Orthogonal experi-mental design was adopted,dry extract rate as evaluation index,to optimize water extraction technology,contents of asperosaponin;naringin and dry extract as evaluation index,to optimize ethanol extraction technology. Results Opti-mal water extraction technology was extracted 2 times with 6 times the amount of water for 1 h per time;optimal etha-nol extraction technology was extracted 3 times with 6 times the amount of 60% ethanol for 2 h per time. Conclusion This optimized extraction technology was stable,feasible,suitable for Buzheng Xugu Granules production. |
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| Keywords: | Buzheng Xugu granules asperosaponin naringin orthogonal experimental design |
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