中医药治疗强直性脊柱炎机制的实验研究进展

强直性脊柱炎（AS），病位主要为督脉、膀胱经、肾经循行所在部位。肾虚是 AS 发病的根本原因，风、寒、湿是发病的重要诱因，痰浊瘀血是发病的关键病因。中医药治疗本病以滋补肝肾、祛寒除湿、化痰逐瘀、活血解毒为主要方法，作用机制多与抗炎镇痛、免疫抑制相关，目前的实验结果表明中医药能有效缓解 AS 的症状，调节相关生物学指标，因此，对实验研究进行总结将为进一步探讨中医药治疗 AS 的机制提供基础。

Mechanism of traditional Chinese medicine on ankylosing spondylitis

Ankylosing spondylitis(AS),mainly on governor meridian,urinary bladder meridian and kidney channel;Kidney deficiency is the fundamental cause of AS,wind,cold and humidity are important causes of the disease, phlegm and blood stasis are the key pathogenesis. Nourishing the liver and kidney,removing the cold、dampness、phlegm and stasis,promoting blood circulation and detoxication are the main methods in treating the disease. The mechanism is related to anti - inflammatory and analgesic effects and immunosuppression. Present experimental results indicate that Chinese medicine can effectively relieve symptoms of AS and regulate related biological index. There-fore,summarize the experimental research will provide a wide idea to further explore the mechanism of traditional Chi-nese medicine in treating AS.