| 应用振动探针技术观察ATP对外沟细胞吸收阳离子的影响 |
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| 引用本文： | 唐玥玓,Daniel C.Marcus,梁传余,安惠民,Toshihiko Chiba.应用振动探针技术观察ATP对外沟细胞吸收阳离子的影响[J].听力学及言语疾病杂志,2002,10(3):167-169. |
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| 作者姓名： | 唐玥玓 Daniel C.Marcus 梁传余 安惠民 Toshihiko Chiba |
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| 作者单位： | 1. 四川大学附属华西医院耳鼻咽喉科学研究室,成都,610041
2. 美国儿童城国家研究医院 |
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| 摘 要： | 目的：研究外沟上皮细胞对维持耳蜗内淋巴环境稳态的作用。方法：应用振动探针技术记录内耳外沟上皮细胞附近的电流密度，并观察ATP对它的作用。结果：在外沟细胞附近记录到负电流，并且该电流在浴液中加入ATP时增加。结论：外沟细胞通过再吸收阳离子以维持耳蜗内淋巴环境的稳态，细胞外ATP能激活它的这种吸收作用。
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| 关 键 词： | 振动探针技术 ATP 外沟上皮细胞 耳蜗 |
| 文章编号： | 1006-7299(2002)03-0167-03 |
| 修稿时间： | 2001年12月13 |
Preliminary Study on Cochlear Outer Sulcus Epithelium Cells By Vibrating Probe Technology |
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| Daniel C.Marcus,Toshihiko Chiba.Preliminary Study on Cochlear Outer Sulcus Epithelium Cells By Vibrating Probe Technology[J].Journal of Audiology and Speech Pathology,2002,10(3):167-169. |
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| Authors: | Daniel CMarcus Toshihiko Chiba |
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| Abstract: | Objective To investigate the role of outer sulcus epithelium cells to the endolymph homeostasis.Methods Vibrating probe technology was used to record current density from outer sulcus epithelium cells and determine the effect of ATP on it.Results The negative current was recorded from outer sulcus epithelium cells .Conclusion This finding demonstrated that outer sulcus epithelium cells contributed to the endolymph homeostasis by reabsorption of cation,and extracellular ATP stimulated this reabsorption. |
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| Keywords: | Vibrating probe technology Outer sulcus epithelium cells ATP |
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