模型生命表方法在出生缺陷患者预期寿命估算中的应用——以唐氏综合征为例

以唐氏综合征为例,研究采用Brass-Logit模型生命表的原理,通过美国一般人群的生命表、美国唐氏综合征患者的生命表、中国一般人群的生命表,间接估算中国唐氏综合征患者的生命表和预期寿命.经过与其他国家一般人群和唐氏综合征人群预期寿命的比较,研究认为,用Brass-Logit模型生命表原理来推算出生缺陷患者的生存状况和预期寿命,是在某一国家或地区的出生缺陷患者存活的数据非常缺乏、而另一些国家已有比较系统数据的情况下可以考虑使用的方法.

Study on the use of model life tables methodology in birth defect''s life expectancy estimation:the case of Down''s syndrome

Using Brass-Logit model and life tables for general population and Down's syndrome patients in U.S.A and life tables for general population in China, we estimated the life table of Down's syndrome patients in China. Through comparing with data from other countries, we suggested that Brass-Logit Model Life Table could be adopted were minimum data of birth defects survival was available and systematic data was handy in another areas.