| P_(16)基因缺失与子宫内膜癌发生机理初探 |
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| 引用本文： | 申元英,杨占秋,钟建勋.P_(16)基因缺失与子宫内膜癌发生机理初探[J].大理医学院学报,1998(4). |
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| 作者姓名： | 申元英 杨占秋 钟建勋 |
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| 作者单位： | 大理医学院微生物教研室(申元英)，湖北医科大学病毒所(杨占秋)，云南省文山卫校生化教研室(钟建勋) |
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| 摘 要： | 目的：探讨Ｐ１６基因与子宫内膜癌发生的关系。方法：采用ＰＣＲ方法，对２０份子宫内膜癌组织标本和１０份子宫肌瘤组织标本的核酸进行扩增。结果：２５％的子宫内膜癌标本（５／２０）有Ｐ１６基因纯合子缺失，而子宫肌瘤组织中无Ｐ１６基因纯合子缺失。结论：Ｐ１６基因缺失与子宫内膜癌有关
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| 关 键 词： | P_(16)基因 子宫内膜癌 PCR |
A Study on P 16 Gene Deletion and Endometrimal Carcinogenesis |
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| Shen,Yuanying,et,al.A Study on P 16 Gene Deletion and Endometrimal Carcinogenesis[J].Journal of Dali Medical College,1998(4). |
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| Authors: | Shen Yuanying et al |
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| Abstract: | Objective:To study the relationship between P 16 gene deletion and endometrimal carcinogenesis.Method:Using PCR to amplify 20 endometrimal carcinoma and 10 endometria specimens.Result:Homozygote deletion was proved in 25% of the endometrimal carcinoma specimens but not in ehdometria.Conclusion:Homozygote deletion of P 16 may be related to endometrimal carcinogenesis. |
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| Keywords: | P 16 gene Endometrimal Carcinoma PCR |
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