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Neuronal cell death induced by antidepressants: lack of correlation with Egr-1, NF-kappa B and extracellular signal-regulated protein kinase activation
Authors:Bartholomä Pia  Erlandsson Nina  Kaufmann Katrin  Rössler Oliver G  Baumann Bernd  Wirth Thomas  Giehl Klaus M  Thiel Gerald
Affiliation:Department of Medical Biochemistry and Molecular Biology, University of Saarland Medical Center, D-66421 Homburg, Germany.
Abstract:
Keywords:dbcAMP, N,2′-O-dibutyryladenosine-3:5-cyclic monophosphate   Egr-1, early growth response 1   ERK, extracellular signal-regulated protein kinase   IBMX, isobutyl-1-methylxanthine   MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide   TCA, tricyclic antidepressants   TUNEL, terminal deoxynucleotidyl transferase fluorescein-dUTP 3′-end labeling.
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