肿瘤血管生成中VEGF/VEGFRs的分子影像进展

肿瘤的血管生成在肿瘤的生长、演进、转移过程中具有重要的调节作用.对新生血管生成过程进行分子影像学评价,有利于肿瘤的早期诊断、指导抗血管药物治疗、估计预后等作用.本文主要对血管内皮生长因子/受体在分子成像中的应用及进展进行综述.

Molecular Imaging of VEGF/VEGFRs in Tumor Angiogenesis

Tumor angiogenesis is a critical requirement during cancer progression. Molecular imaging techniques can allow for much earlier diagnosis and better prognosis, which will eventually lead to per-sonalized molecular medicine. In this review, we will summarize the progress to date on molecular imaging of tumor angiogenesis, which focusing on the vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR).