Advances in atopic dermatitis |
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Authors: | Novak Natalija Leung Donald Y M |
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Affiliation: | 1Department of Dermatology and Allergy, University of Bonn, Sigmund-Freud Str. 25, D-53105 Bonn, Germany;2Department of Pediatrics, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA |
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Abstract: | Atopic dermatitis (AD) results from barrier defects combined with modified immune responses of the innate and the adaptive immune system to exogenous and endogenous factors. Recent research has continued to sort out the complex pathophysiologic puzzle of this frequent skin disease. However, the network of mechanisms leading to the manifestation of AD is far from being completely understood. |
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