Beware the lymphopenia: a case of severe combined immunodeficiency |
| |
Authors: | Mehr Sam Kakakios Alyson Shaw Peter Webster Richard Kemp Andrew |
| |
Affiliation: | Department of Allergy and Immunology, The Children's Hospital at Westmead, Sydney, New South Wales, Australia. samm@chw.edu.au |
| |
Abstract: | We present a case of a 2-month-old boy with partially treated meningitis and suspected Pneumocystis carinii pneumonia. A full blood count revealed profound lymphopenia. The child was diagnosed with adenosine deaminase deficiency, a rare cause of severe combined immunodeficiency (SCID). SCID is an immunological emergency and must be considered in any lymphopaenic infant with opportunistic infection. We discuss adenosine deaminase-deficient SCID, which can involve multiple systems and in which other treatment options apart from bone marrow transplant are available. |
| |
Keywords: | adenosine deaminase lymphopenia SCID |
本文献已被 PubMed 等数据库收录! |
|